The Rarest Cancer is Sarcomatoid mesothelioma.
Mesothelioma can be categorized broadly as: epithelial, sarcomatoid and biphasic.
Sarcomatoid mesothelioma is the rarest form of cancer, affecting only 10-20% of patients. In this type of mesothelioma, cells transform as spindle-shaped pattern that overlap each other and occurs from support tissues such as cartilage, muscle, bone and fat. When the cancer is only on the membrane surface it can be known as Localized mesothelioma. In advanced stages, it might spread beyond the original membrane surface to other parts of the body, such as the lungs, lymph nodes, chest wall, or abdominal organs.
Sarcomatoid mesothelioma Symptoms:
Symptoms of mesothelioma might appear several decades after exposure to asbestos. The most common are severe pain due to fluid retention in the pleural area, spinal swelling and cough, weight loss and accumulation of fluid in abdominal cavity, blood clotting abnormality, anemia, and fever are other symptoms.
How to diagnose Sarcomatoid mesothelioma:
Sarcomatoid mesothelioma, is diagnosed by extraction of affected tissue during biopsy, it is usually difficult because symptoms of mesothelioma are similar to those of other diseases. Response to treatment is poor, which might result in fatality within a year of diagnosis.